The Aurum Rustenburg Clinical Research Site (CRS) is situated in the Bojanala Platinum District of the North West (NW) Province, South Africa, approximately 103km from Johannesburg. The district with approximately 1 507 505 inhabitants and consist of 4 sub-districts. The Rustenburg sub-district where the Rustenburg CRS is located is infamous for its wealth of Platinum mining and mining of other mineral elements. The Rustenburg sub-district is the largest with 549 575 people (3423.26 km²). A growing mining industry over the past two decades has resulted in many migrant populations relocating to Rustenburg in search of employment, making Rustenburg one of the fastest growing cities in South Africa.
About The Research Centre
The site is closely located to the Job Shimankana Tabane hospital (< 1km), which is the only level 2 hospital in the Bojanala district. The hospital is comprised of 21 wards, which house 460 beds. Furthermore, the hospital encompasses an MDR unit and makes it the 3rd hospital in the Province catering for MDR patients. The hospital receives referrals from the surrounding health care centres and the level 1 hospitals. The hospital is also satellite hospital for training undergraduate and postgraduate medical students from the University of Limpopo. The Rustenburg sub-district has 24 Department of Health clinics.
The Rustenburg CRS has been in operation since 2007 and has been engaged in both NIH-related work (HIV Vaccine Trial Network (HVTN) 913 study) and non-NIH related work. The site has the capacity to enrol 300-500 participants over 12 months.
Aurum’s Rustenburg centre is renowned for its excellent clinical research management capabilities.
The centre’s mission is to improve the health of disadvantaged people by providing care through research. The centre focuses on three key research areas:
- HIV prevention Research
- TB Treatment Research
- TB Prevention Research
The North-West Province ranks as the fourth highest province in terms of its burden of HIV (13.9%1 (95%CI:12.0-16.1). The North-West provincial HIV prevalence amongst antenatal women in 2012 was 29.7% (95% CI:27.5-32.0)2. The same data for the Bojanala District suggests HIV seroprevalence was 33.9% (95%CI:30.4-37.6) in 2011 and 35.0% (95%CI:24.7-34.0) in 2012 We have estimated HIV incidence in Rustenburg, using observational cohort studies.
Research Outputs From Aurum Rustenburg Clinical Research Centre
Some of the publications produced by the Rustenburg Clinical Research Centre:
- Feldblum PJ, et al. HIV incidence and prevalence among cohorts of women with higher risk behaviour in Bloemfontein and Rustenburg, South Africa: a prospective study. BMJ Open. 2012 Feb 13;2(1):e000626
- Chetty-Makkan CM, et al. Pregnancy incidence and correlates in a clinical trial preparedness study, north-west province South Africa. PLoS One. 2014 May 6;9(5):e9570
- Kamali A, et al. Creating an African HIV Clinical Research and Prevention Trials Network: HIV Prevalence, Incidence and Transmission PLoS One. 2015