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Implementation Research

Featured news on Implementation Research

panTB-HM Study AGM Marks Five Years of Progress

The panTB-HM Study Annual General Meeting (AGM) brought together partners, researchers, and site teams to reflect on fiv...

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Our Implementation Research Division is responsible for conducting health research and scientific evaluations in the area of HIV and TB prevention, care, and treatment.

We are a multi-disciplinary group that applies scientific inquiry into questions concerning the implementation of policies, programmes or practices that contribute to national, regional and global strategies and targets.

Our Pillars

Innovative Impactful Implementation Research

Conducting research that addresses critical health challenges to generate new knowledge and solutions in TB, HIV, and COVID-19 care in underserved regions. Bridging the gap between research interventions and pragmatic application to ensure fit for purpose health innovations that are feasible, accessible, and acceptable to patients, communities, and health care providers.

Global and Local Partnerships and Collaboration

Establishing and strengthening collaborations with international and local stakeholders, including academic institutions, governments, non-governmental organizations, and communities to enhance the reach, relevance, cultural appropriateness, and impact of research initiatives.

Quality Publications

Maintaining a robust output of peer-reviewed publications that contribute to the global body of knowledge and influence health policies and practice.

Evidence Based Policy

Translating research findings into actionable policies that improve health outcomes and inform public health strategies.

Capacity Building

Training and mentoring the current and next generation of researchers, policymakers, and practitioners in implementation science and public health

Sustainable Scalable Solutions

Developing and promoting interventions that are not only effective but also sustainable and scalable in diverse health systems and contexts

We study various approaches to translate effective interventions into health care policy and practice.

We use a variety of disciplines including epidemiology, biostatistics, health policy, health economics, management sciences, sociology, psychology and others to identify, develop and measure the impact of innovative strategies to improve HIV and TB service delivery.

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"We innovate and disseminate TB, HIV, and COVID-19 research, and translate our findings to actionable impactful policies that aim to improve health outcomes in our communities."

Prof. Geoffrey Setswe
Managing Director: Implementation Research Division

Our Team

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Professor Geoffrey Setswe

Managing Director
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Dr Tonderai Mabuto

Director: HIV Research
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Nontobeko Ndlovu

Head of Department Research Projects

Latest Research Studies

Located near Rustenburg’s platinum mines, this research hub will focus on the social and health effects of mining and migration on local communities. Led by the AWISE collaboration—a partnership including Aurum Institute, Wits University, Sefako Makgatho University of Health Sciences, and Johns Hopkins University—the BAMMISHO Node is set to gather robust, long-term data on health, migration, and demographic patterns in the Bojanala District.

TB SEQUEL 2

Aurum co-leads and is the African coordinating partner for the TB-Sequel project, a pan-African project to understand the clinical, microbiologic, and host immune factors affecting or predicting the long-term sequelae and socio-economic impact of pulmonary tuberculosis and treatment outcome, taking place in Tanzania, The Gambia, Mozambique and South Africa.

2wT study

This study tests an mHealth intervention to reduce VMMC follow-up workload while preserving patient safety. Researchers will use two-way mobile phone texts to provide in-person review only for men who indicate a desire or need for follow-up. Text-based, post-procedure VMMC care could reduce unnecessary visits and remove barriers for VMMC clients without reduction in quality care. Reduced in-person follow-up could also free healthcare workers to perform additional VMMC surgeries.
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Aurum also leads global research trials such as the WHIP3TB trial - a randomized trial evaluating the use of the 3HP regimen for PLHIV given annually - which is funded by the Challenge TB mechanism.

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CUT-TB (Community and Universal Testing for TB among contacts) is a 4-year EDCTP funded cluster-randomised pragmatic that is being conduct in South Africa, Tanzania and Lesotho. The study aims to measure effectiveness of universal testing compared to standard TB screening for detection of TB among household and community contacts.

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The Opt4TPT (Optimising the delivery cascade for tuberculosis preventive treatment among people living with HIV) study is a three-year programmatic assessment of TPT delivery across three countries, namely Ethiopia, South Africa and Zimbabwe, to generate critical knowledge to improve TPT uptake, implementation and outcomes

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