Tuberculosis - The Aurum Institute

Healthcare costs pushing more than half of SA’s TB patients into poverty

South Africa's TB crisis is not just a health issue but an economic and social one, as new research commissioned by the National South African Health Department (DOH) reveals. The study highlights tha...
Healthcare costs pushing more than half of SA’s TB patients into poverty

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Diagnosis of tuberculosis infection in children with a novel skin test and the traditional tuberculin skin test: An observational study

Fritschi, N., Gureva, T., Eliseev, P., Jackson, C., Milanzi, E., Crichton, S., Collins, I.J., Turkova, A., Mariandyshev, A. and Ritz, N., 2024. Diagnosis of tuberculosis infection in children with a n...
Effect of digital adherence technologies on treatment outcomes in people with drug-susceptible tuberculosis:

Four pragmatic, cluster-randomised trials Jerene, D., van Kalmthout, K., Levy, J., Alacapa, J., Deyanova, N., Dube, T., Mganga, A., Tasca, B., Bogdanov, A., Efo, E. and Gamazina, K., 2025. Effect o...
Aurum's Community Engagement Manager joins Global TB Advisory Board

The Aurum Institute is proud to announce that Blossom Makhubalo, our Community Engagement Manager, has been appointed as one of the newest members of the Global Tuberculosis Community Advisory Board (...
What is next for BCG revaccination to prevent tuberculosis?

White, R.G., Fiore-Gartland, A.J., Hanekom, W.A., Vekemans, J., Garcia-Basteiro, A.L., Churchyard, G., Rangaka, M.X., Frick, M., Behr, M.A., Hill, P.C. and Mave, V., 2024. What is next for BCG revacci...
A phase IIb, open-label, randomized controlled dose ranging multi-centre trial to evaluate the safety, tolerability, pharmacokinetics and exposure-response relationship of different doses of delpazolid in combination with bedaquiline delamanid moxifloxacin in adult subjects with newly diagnosed, uncomplicated, smear-positive, drug-sensitive pulmonary tuberculosis.

Dierig, A., Hoelscher, M., Schultz, S., Hoffmann, L., Jarchow-MacDonald, A., Svensson, E.M., Te Brake, L., Aarnoutse, R., Boeree, M., McHugh, T.D. and Wildner, L.M., 2023. A phase IIb, open-label, ran...
. Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses.

Krause, R., Warren, C.M., Simmons, J.D., Rebeiro, P.F., Maruri, F., Karim, F., Sterling, T.R., Koethe, J.R., Leslie, A. and Van der Heijden, Y.F., 2023. Failure to decrease HbA1c levels following TB t...
A qualitative exploration into the presence of TB stigmatization across three districts in South Africa.

DeSanto, D., Velen, K., Lessells, R., Makgopa, S., Gumede, D., Fielding, K., Grant, A.D., Charalambous, S. and Chetty-Makkan, C.M., 2023. A qualitative exploration into the presence of TB stigmatizati...
TB preventive therapy preferences among children and adolescents.

Strauss, M., Wademan, D.T., Mcinziba, A., Hoddinott, G., Rafique, M., Jola, L.N., Streicher, C., du Preez, K., Osman, M., Boffa, J. and Hausler, H., 2023. TB preventive therapy preferences among child...
IFN-γ independent markers of mycobacterium tuberculosis exposure among male South African gold miners.

Davies, L.R., Smith, M.T., Cizmeci, D., Fischinger, S., Lee, J.S.L., Lu, L.L., Layton, E.D., Grant, A.D., Fielding, K., Stein, C.M. and Boom, W.H., 2023. IFN-γ independent markers of Mycobacterium tu...
Accelerate 1 Programme Highlights Community-Centric Health Solutions in Gqeberha

Aurum in collaboration with the Eastern Cape Department of Health, had the privilege of welcoming USAID representatives to the KwaZakhele Community Health Centre in Gqeberha, Nelson Mandela Bay metro....
Highlights from the Union World Conference on Lung Health 2024

The Union World Conference on Lung Health 2024 in Bali brought together over 4,000 delegates from around the world to share groundbreaking research and initiatives addressing lung health. The Aurum In...
DRTB-HDT Annual Consortium Meeting

The DRTB-HDT Annual Consortium Meeting brought together global collaborators, reflecting on achievements and outlining strategies for the upcoming year. Hosted by The Aurum Institute, the event conclu...
World TB Day 2025: Mothers and Children at the Heart of TB Prevention

When Cyprion Mpume Makhanya learned about the DOLPHIN Moms clinical trial, she was pregnant with her daughter and fearful of the unknown. Could participating in the study really protect her baby from ...