Clinical Research
Running clinical trials ranging from large scale public health studies, to highly regulated clinical trials of new medications.
Each clinical research site (CRS) brings a unique complement of skills, populations, facilities, and experience.
We have conducted more than 210 research studies and clinical trials at 5 main Clinical Research Centres in Klerksdorp, Rustenburg, Tembisa, Pretoria and Mozambique.
Conducted > 210 trials and research studies in the past 18 years focusing on:
HIV vaccines & prevention (oral, topical, and long-acting injectable PrEP)
TB treatment, Host-directed therapy, TB vaccines & TB preventative therapy
COVID-19 vaccines, COVID-19 mAb & COVID-19 treatment
Diagnostics and socio-behavioral studies.
Enrolled > 66 500 participants in trials and research studies (Clinical Research Division)
More than 23 500 Thibela TB (enrollment at mine shafts)
More than 25 500 Sisonke vaccine roll-out to Healthcare Workers (enrollment at Department of Health Vaccination Sites)
More than 17 500 enrolled in remaining trials and research studies (enrollment at 6 Clinical Research Sites)
Aurum’s distinct strengths:
CRS pluripotency
Collective scientific, operational & management experience of its research leadership
High-functioning resources & systems to effectively implement large-scale complex clinical trials (both network & Investigator-lead)
We focus on these programmatic areas:
COVID-19
HIV Treatment & PreP
TB Treatment
HIV Vaccine
TB Vaccine
Special Projects
2022 AT A GLANCE
276
Employees
6
Clinical Research Sites
1
Overnight / PK facility
3
Routine Laboratories
1
Basic Research Lab which includes a BSL-3 mycobacteriology lab
1
Biorepository
4
Registered Pharmacies
26
Funders
54
Clinical Trials Conducted in 2022
4713
Participants
26
Vaccine Trials
28
Treatment & Prevention Trials
11
Aurum Led Trials
34
CRD Publications:
Aurum CRS Centres
Pretoria CRS
Acquired to conduct Pharma & PK Trials.
78 trials > 3 300 enrolled.
78 trials > 3 300 enrolled.
Fundação Aurum
Established in Mozambique to aid roll out of 3HP & Covid-19 self-testing and prepare for TPT Phase 3 and 4 trials.
1 trials > 18 enrolled.
1 trials > 18 enrolled.
Tembisa CRS
Established to conduct TB Treatment Trials Consists of 2 CRS’s (C1&2, C3&4)
C1&2: 41 Studies/Trials > 3 300 enrolled.
C3&4: 11 Studies/Trials > 2 100 enrolled.
C1&2: 41 Studies/Trials > 3 300 enrolled.
C3&4: 11 Studies/Trials > 2 100 enrolled.
Rustenburg CRS
Established to conduct HIV Epidemiology Studies to prepare for HIV Vaccine Trials.
44 trials > 16 600 enrolled.
44 trials > 16 600 enrolled.
Klerksdorp CRS
Established to conduct HIV Vaccine Trials.
43 trials > 16 600 enrolled.
43 trials > 16 600 enrolled.
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We have seen the impact of clinical trials saving millions of lives in the COVID-19 pandemic and we are now even more committed to continue our search for safer, more effective tools to address the continuing TB and HIV pandemics!
Our Team
Tanya Nielson
Managing Director: Clinical Research Division
Dr Craig Innes
Clinical Director: Clinical Research Division
Sharfuddin Sayed
Operations Director: Clinical Research Division
Dr William Brumskine
Clinical Research Site Leader: Rustenburg
Dr Kathy Mngadi
Clinical Research Site Leader: Tembisa
Dr Pearl Selepe
Clinical Research Site Leader: Klerksdorp
Trevor Beattie
Head of Department: CRD Projects
Lindiwe Nhlangulela
Head of Department: Laboratory
John Mdluli
Head of Department: Community
Naydene Slabbert
Head of Department: Data Management
Latest Highlights
Read the latest news about our work in clinical research
